Unlock the Full Potential of Organoids with HT
Holotomography imaging – the game changing tool for precision medicine and drug discovery
Label-free imaging
HT imaging does not require any labeling or staining, therefore provides more reliable and relevant information.
High resolution 3D imaging
HT generates high quality, meaningful data by resolving spatial and long-term, temporal detail.
Timelapse imaging
HT allows real-time imaging of organoids in their natural states, enabling the observation of their behavior and dynamic over time.
Downstream analysis
After HT imaging, researchers can return live organoids sample to the incubator for further observation or downstream analysis.
Simplified sequential workflow
HT enables more efficient experiments by reducing time-consuming preparation steps and chemicals used.
Cost effective
HT reduces the general cost of experimentation by minimizing labor cost, time expense and sample damages.
3D Organoid Imaging and Analysis Workflow
Conventional workflow
Continuous workflow with Tomocube HT-X1
Tomocube HT-X1 - Extra features for your best outcome
Fluoresence microscope
Tomocube HT-X1
High resolution 3D imaging
Fluorescence imaging
Timelapse
Subcellular structure visualization
Minimal sample toxicity
Non invasive imaging
Downstream analysis
convenient workflow
3D Imaging of Organoids
Human Lung Organoid
Fixed lung organoid captured by the HT-X1. The image was taken after the organoid was resuspended in PBS, placed at Tomodish and covered with a coverslip.
Human Liver Organoid
Fixed human liver organoid captured by the HT-X1. Diverse subcellular-level features of individual cells such as nucleus, nucleoli, mitochondria, vacuoles, and granules are visible.
Mouse Small Intestinal Organoid
The 3D structure of a mouse small intestinal organoid was captured by HT-X1. This video shows diverse microscale features the intestinal organoid such as lumen, epithelium, paneth cells, and goblet cells.
Mouse Small Intestinal Organoid
Label-free imaging video of a mouse small intestinal organoid growing in Matrigel for 5 days in its native state. Holotomography video was post-processed to enhance visualization by color-coded projection technique.
Quantitative Analysis
Quantitative analysis of organoid growth for 5 days
