Publications

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Label-free monitoring of 3D cortical neuronal growth in vitro using optical diffraction tomography

Ariel J. Lee, DongJu Yoon, […] YoonKey Nam, YongKeun Park, Biomedical Optics Express (2021)

Sinking of Four Species of Living Diatom Cells Directly Observed by a “Tumbled” Optical Microscope

Ryp Hamano, Shingo Shoumura, […] , Han-Jia Lin, Kazuo Umemura, Microscopy and Microanalysis (2021)

Label-Free Quantitative Analysis of Coacervates via 3D Phase Imaging

Yuri Hong, Khoi Phuong Dao, Taehyun Kim, Sumin Lee, Yongdae Shin, YongKeun Park, Advanced Optical Materials (2021)

Three-dimensional label-free visualization and quantification of polyhydroxyalkanoates in individual bacterial cell in its native state

So young Choi, Jeonghun Oh, JaeHwang Jung, YongKeun Park and Sang Yup Lee, PNAS (2021)

DeepRegularizer: Rapid Resolution Enhancement of Tomographic Imaging Using Deep Learning

DongHun Ryu, Dongmin Ryu, […] , Hyun-Seok Min, Yongkeun Park, IEEE Transaction on Medical Imaging (2021)

Label-free tomographic imaging of nanodiamonds in living cells

Dini Kurnia Ikliptikawati, Masaharu Hazawa, […] , Masahiro Shirakawa, Richard W. Wong, Diamond and Related Materials (2021)

Multiscale label-free volumetric holographic histopathology of thick-tissue slides with subcellular resolution

Herve Hugonnet, Yeon Wook Kim, […] , Seung-Mo Hong, YongKeun Park, Advanced Photonics (2021)

CD45 pre-exclusion from the tips of T cell microvilli prior to antigen recognition

Yunmin Jung, Lai Wen, Amnon Altman & Klaus Ley, Nature Communications (2021)

New Multiscale Characterization Methodology for Effective Determination of Isolation–Structure–Function Relationship of Extracellular Vesicles

Thanh Huyen Phan, Shiva Kamini Divakarla, […] , Yoon-Kyoung Cho, Wojciech Chrzanowski, frontiers (2021)

Super-resolution imaging reveals cytoskeleton-dependent organelle rearrangement within platelets at intermediate stages of maturation

Seokran Go, Dokyung Jeong, […] , Yang Hoon Huh, Doory Kim, Structure (2021)

Isotropically resolved label-free tomographic imaging based on tomographic moulds for optical trapping

Moosung Lee, Kyoohyun Kim, Jeonghun Oh, YongKeun Park, Light: Science & Applications (2021)

Super-resolution imaging of platelet-activation process and its quantitative analysis

Jinkyoung Chung, Dokyung Jeong, […] , Yang Hoon Huh, Doory Kim, Scienctific Reports (2021)

Immunization with RBD-P2 and N protects against SARS-CoV-2 in nonhuman primates

So-Hee Hong, Hanseul Oh, […] , Eun Young Oh, Hyo-Jung Park, Science Advances (2021)

Detection of intracellular monosodium urate crystals in gout synovial fluid using optical diffraction tomography

Sangwoo Park, Lucy Eunju Lee, […] , Jason Jungsik Song, Seongsoo Lee, scientific reports (2021)

Label-free three-dimensional analyses of live cells with deep-learning-based segmentation exploiting refractive index distributions

Jinho Choi, Hye-Jin Kim, […] , Hyunseok Min, YongKeun Park, BioRxiv (2021)

Optimization of DMD-based independent amplitude and phase modulation: a spatial resolution and quantization

Alexandra Georgieva, Andrey Belashov, Nikolay V. Petrov, arXiv (2020)

Reagent- and actuator-free analysis of individual erythrocytes using three-dimensional quantitative phase imaging and capillary microfluidics

DongHun Ryu, Hyeono Nam, Jessie S. Jeon, YongKeun Park, bioRxiv (2021)

Refractive Index Changes of Cells and Cellular Compartments Upon Paraformaldehyde Fixation Acquired by Tomographic Phase Microscopy

Maria Baczewska, Kai Eder, […] , Björn Kemper, Małgorzata Kujawińska, ISAC (2020)

Iterative optical diffraction tomography for illumination scanning configuration

Shengli Fan, Seth Smith-Dryden, Guifang Li, and Bahaa Saleh, Optics Express (2020)

Chemotherapy confers a conserved secondary tolerance to EGFR inhibition via AXL-mediated signaling bypass

Mark Borris D. Aldonza, Roben D. Delos Reyes, […] , Je-Yoel Cho, Yoosik Kim, Scientific Reports (2021)

Holographic tomography: techniques and biomedical applications

Vinoth Balasubramani, Arkadiusz Kuś, […] , Wojciech Krauze, and Małgorzata Kujawińska, OSA Publishing (2021)

Correlation of dynamic membrane fluctuations in red blood cells with diabetes mellitus and cardiovascular risks

Minji Sohn, Ji Eun Lee, […] , YongKeun Park, Soo Lim, scientific reports (2021)

New multiscale characterisation methodology for effective determination of isolation-structure-function relationship of extracellular vesicles

Thanh Huyen Phan, Shiva Kamini Divakarla, […] , Yoon-Kyoung Cho, Wojciech Chrzanowski, bioRxiv (2021)

Fabrication and Characterization of Human Serum Albumin Particles Loaded with Non-Sericin Extract Obtained from Silk Cocoon as a Carrier System for Hydrophobic Substances

Kanyaluck Jantakee, Ausanai Prapan, […] , Yingmanee Tragoolpua, Hans Bäumler, Polymers (2021)

3D Fourier transformation light scattering for reconstructing extend angled resolved light scattering of individual particles

Khoi Phuong Dao, Kyeoreh Lee […] YongKeun Park, arXiv (2021)

TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis

Mark Esposito, Cao Fang, […] , Ileana M. Cristea & Yibin Kang, Nature Cell Biology (2021)

3D cell instance segmentation via point proposals using cellular components

Jinho Choi, Junwoo Park, […] , Sungbin Lim, Jaegul Choo, SPIE-PW(Photonic West) BiOS (2021)

Coarse Raman and optical diffraction tomographic imaging enable label-free phenotyping of isogenic breast cancer cells of varying metastatic potential

Santosh Kumar Paidi, Vaani Shah, […] , Rishikesh Pandey & Ishan Barman, Biosensors and Bioelectronics (2021)

Optimizing sample illumination scanning in transmission tomographic diffractive microscopy

Asemare Mengistie Taddese, Nicolas Verrier, […] , Jean-Baptiste Courbot, and Olivier Haeberlé, Applied Optics (2021)

Optimizing illumination in three-dimensional deconvolution microscopy for accurate refractive index tomography

Herve Hugonnet, Moosung Lee, and YongKeun Park, Optics Express (2021)

Nanocharacterisation of extracellular vesicles uncovers the correlation between isolation methods, physicochemical composition and their biological function

Thanh Huyen Phan, Shiva Kamini Divakarla, […] , Yoon-Kyoung Cho, Wojciech Chrzanowski, bioRxiv (2021)

Intensity-based holographic imaging via space-domain Kramers–Kronig relations

YoonSeok Baek & YongKeun Park, Nature Photonics (2021)

Label-free three-dimensional observations and quantitative characterisation of on-chip vasculogenesis using optical diffraction tomography

Chungha Lee, Seunggyu Kim, […] Jessie S. Jeon, YongKeun Park, Lab on a Chip (2021)

Spatiotemporally tracking of nano-biofilaments inside the nuclear pore complex core

Mahmoud Shaaban Mohamed, Masaharu Hazawa, […] , Toshio Ando, Richard W.Wong, Biomaterials (2020)

Structure, self-assembly, and properties of a truncated reflectin variant

Mehran J. Umerani, Preeta Pratakshya […] Yaroslava G. Yingling, and Alon A. Gorodetsky, PNAS (2020)

Camphene Attenuates Skeletal Muscle Atrophy by Regulating Oxidative Stress and Lipid Metabolism in Rats

Suji Baek, Jisu Kim […] Bom Sahn Kim & Kang pa Lee, nutrients (2020)

Disease-specific alteration of karyopherin-α subtype establishes feed-forward oncogenic signaling in head and neck squamous cell carcinoma

Masaharu Hazawa, Kie Sakai […] De-Chen Lin & Richard W. Wong, Oncogene (2020)

Quantitative Optical Diffraction Tomography Imaging of Mouse Platelets

Tess A. Stanly, Rakesh Suman […] Paul M. Kaye and Ian S. Hitchcock, Front. Physiol (2020)

Label-free imaging and analysis of subcellular parts of a living diatom cylindrotheca sp. using optical diffraction tomography

Kazuo Umemura, Yuji Matsukawa […] Shigeki Mayama, MEthodsX (2020)

Self-luminescent photodynamic therapy using breast cancer targeted proteins

Eun Hye Kim, Sangwoo Park […] Young-Pil Kim, Science Advances (2020)

Improved Erythrocyte Deformability Induced by Sodium-Glucose Cotransporter 2 Inhibitors in Type 2 Diabetic Patients

Minkook Son, Ye Sung Lee […] Ho-Cheol Kang, Sung Yang, Cardiovascular Drugs and Therapy (2020)

Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes

Won Hoon Choi, Yejin Yun […] Sang Min Lim, Min Jae Lee, PNAS (2020)

Intercellular Bioimaging and Biodistribution of Gold Nanoparticle-Loaded Macrophages for Targeted Drug Delivery

Sehwan Kim, Sung Hun Kang […] Seok Jin Hong, Electronics (2020)

Platelet thrombus formation by upstream activation and downstream adhesion of platelets in a microfluidic system

Sihui Xu, Jinxiang Piao […] Sehyun Shin, Biosensors and Bioelectronics (2020)

Protein-Bound Polysaccharides from Coriolus Versicolor Induce RIPK1/RIPK3/ MLKL-Mediated Necroptosis in ER-Positive Breast Cancer and Amelanotic Melanoma Cells

Małgorzata Pawlikowska, Tomasz Jędrzejewski […] Sylwia Wrotek, Cellular Physiology and Biochemistry (2020)

3D morphological and biophysical changes in a single tachyzoite and its infected cells using three‐dimensional quantitative phase imaging

Egy Rahman Firdaus, Ji‐Hoon Park […] Eun‐Taek Han, Journal of Biophotonics (2020)

Enhanced succinic acid production by Mannheimia employing optimal malate dehydrogenase

Jung Ho Ahn, Hogyun Seo […] Kyung-jin Kim & Sang Yup lee, Nature Communications (2020)

Biomimetic Gold Nanoshell-Loaded Macrophage for Photothermal Biomedicine

Sung Hun Kang, Yong Kyu Lee […] Henry Hirschberg & Seok Jin Hong, BioMed Research International (2020)

Real-time cholesterol sorting in Plasmodium falciparum-erythrocytes as revealed by 3D label-free imaging

Eri H. Hayakawa […] Masahiro Mori & Glenn Nardone, Scientific Reports (2020)

PRMT6-mediated H3R2me2a guides Aurora B to chromosome arms for proper chromosome segregation

Seul Kim, Nam Hyun Kim […] Chang-Young Jang & Yong Kee Kim, Nature Communications (2020)

Microplastics ingestion in the ephyra stage of Aurelia sp. triggers acute and behavioral responses

Elisa Costa, Chiara Gambardella […] Marco Fimali, Ecotoxicology and Environmental Safety (2020)

Label-Free Tomographic Imaging of Lipid Droplets in Foam Cells for Machine-Learning-Assisted Therapeutic Evaluation of Targeted Nanodrugs

Sangwoo Park, Jae Won Ahn […] YongKeun Park, Seongsoo Lee & Kyeongsoon Park, ACS Nano (2020)

Measuring three-dimensional dynamics of platelet activation using 3-D quantitative phase imaging

SangYun Lee, Seongsoo Jang, YongKeun Park, bioRxiv (2019)

Three-dimensional label-free observation of individual bacteria upon antibiotic treatment using optical diffraction tomography

Jeonghun Oh, Jea Sung Ryu […] Hyun Jung Chung, YongKeun Park, bioRxiv (2019)

Mitotic Chromosomes in Live Cells Characterized Using High-Speed and Label-Free Optical Diffraction Tomography

Tae-Keun Kim, Byong-Wook Lee […] Sang-Wook Lee, Chan-Gi Pack, Cells (2019)

Deep learning-based optical field screening for robust optical diffraction tomography

DongHun Ryu, YoungJu Jo […] Hyun-Seok Min & YongKeun Park, Scientific Reports (2019)

A Toolbox for Organelle Mechanobiology Research—Current Needs and Challenges

Qian Feng, Sung Sik Lee and Benoît Kornmann, Micromachines (2019)

Unique Red Blood Cell Morphology Detected in a Patient with Myelodysplastic Syndrome by Three-dimensional Refractive Index Tomography

Se-eun Koo, Seongsoo Jang […] Yongkeun Park, Laboratory Medicine Online (2019)

Reconstruction of bovine spermatozoa substances distribution and morphological differences between Holstein and Korean native cattle using three-dimensional refractive index tomography

Hao Jiang, Jeong-woo Kwon […] Yong-Keun Park & Nam-Hyung Kim, Scientific Reports (2019)

Cycle-consistent deep learning approach to coherent noise reduction in optical diffraction tomography

Gunho Choi, DongHun Ryu […] Hyun-seok Min & YongKeun Park , Optics Express (2019)

In situ measurement of absolute concentrations by Normalized Raman Imaging

Seungeun Oh, ChangHee […] Marc W. Kirschner, bioRxiv (2019)

Optical Measurements of Three-Dimensional Microscopic Temperature Distributions Around Gold Nanorods Excited by Localized Surface Plasmon Resonance

JunTaek Oh, Gu-Haeng Lee […] YongKeun Park, Physical Review Applied (2019)

Rapid and label-free identification of individual bacterial pathogens exploiting three-dimensional quantitative phase imaging and deep learning

Geon Kim, Daewoong Ahn, […] , Nam Yong Lee, YongKeun Park, bioRxiv (2019)

Study of Optical Configurations for Multiple Enhancement of Microalgal Biomass Production

Changsoon Cho, Kibok Nam […] Jong-In Han & Jong-Yong Lee, Scientific Reports (2019)

Deep-learning based three-dimensional label-free tracking and analysis of immunological synapses of chimeric antigen receptor T cells

Moosung Lee, Young-Ho Lee […] Chan Hyuk Kim, YongKeun Park, bioRxiv (2019)

Physicochemical Properties of Chromosomes in Live Cells Characterized by Label-Free Imaging and Fluorescence Correlation Spectroscopy

Tae-Keun Kim, Byong-Wook Lee […] Chan-Gi Pack, bioRxiv (2019)

Label-free high-resolution 3-D imaging of gold nanoparticles inside live cells using optical diffraction tomography

Doyeon Kim, Nuri Oh […] YongKeun Park, Methods (2018)

Low-coherent optical diffraction tomography by angle-scanning illumination

KyeoReh Lee, Seungwoo Shin, Zahid Yaqoob, Peter T.C.So, YongKeun Park, Journal of Biophotonics (2018)

Refractive index as an intrinsic imaging contrast for 3-D label-free live cell imaging

Doyeon Kim, Sangyun Lee […] YongKeun Park, bioRxiv (2018)

Deep-learning-based label-free segmentation of cell nuclei in time-lapse refractive index tomograms

Jimin Lee, Hyejin Kim […] YongKeun Park, Sang Joon Ye, bioRxiv (2018)

Reconstructed Three-Dimensional Images and Parameters of Individual Erythrocytes Using Optical Diffraction Tomography Microscopy

Se-eun Koo, Seongsoo Jang, YongKeun Park, Chan Jeong Park, Annalys of Laboratory Medicine. (2018)

Label-Free Identification of Lymphocyte Subtypes Using Three-Dimensional Quantitative Phase Imaging and Machine Learning

Jonghee Yoon, YoungJu Jo […] YongKeun Park, JoVE (2018)

Combining Three-Dimensional Quantitative Phase Imaging and Fluorescence Microscopy for the Study of Cell Pathophysiology

Young Seo Kim, SangYun Lee […] Sumin Lee and YongKeun Park, Yale J Biol Med. (2018)

Computational Modeling and Clonogenic Assay for Radioenhancement of Gold Nanoparticles Using 3D Live Cell Images

Wonmo Sung, Yoon Jeong […] Sung-Joon Ye, Radiation Research (2018)

Quantitative phase imaging in biomedicine

YongKeun Park, Christian Depeursinge & Gabriel Popescu, Nature Photonics (2018)

Molecular Camouflage of Plasmodium falciparum Merozoites by Binding of Host Vitronectin to P47 Fragment of SERA5

STakahiro Tougan, Jyotheeswara R. Edula […] Takafumi Tsuboi & Toshihiro Horii, Scientific Reports (2018)

Mitochondria-targeting indolizino[3,2-c]quinolines as novel class of photosensitizers for photodynamic anticancer activity

Soonbum Kwon, Yeongcheol Lee […] Ikyon Kim, Jeeyeon Lee, European Journal of Medicinal Chemistry (2018)

Super-resolution three-dimensional fluorescence and optical diffraction tomography of live cells using structured illumination generated by a digital micromirror device

Seungwoo Shin, Doyeon Kim […] Yongkeun Park, Scientific Reports (2018)

Three-dimensional label-free imaging and analysis of Pinus pollen grains using optical diffraction tomography

Geon Kim, Sangyun Lee […] Yongkeun Park, Scientific Reports (2018)

Reconstructions of refractive index tomograms via a discrete algebraic reconstruction technique

Moosung Lee, Seungwoo Shin […] Yongkeun Park, Optics Express (2017)

Measurements of three-dimensional refractive index tomography and membrane deformability of live erythrocytes from Pelophylax nigromaculatus

Geom Kim, Moosung Lee […] YongKeun Park, bioRxiv (2017)

Melittin-induced alterations in morphology and deformability of human red blood cells using quantitative phase imaging techniques

Joonseok Hur, Kyoohyun Kim […] YongKeun Park, Scientific Reports(2017)

Measurements of morphological and biophysical alterations in individual neuron cells associated with early neurotoxic effects in Parkinson’s disease

Su-A Yang, Jonghee Yoon […] YongKeun Park , Cytometry Part A (2017)

Measuring cell surface area and deformability of individual human red blood cells over blood storage using quantitative phase imaging

HyunJoo Park, SangYun Lee […] YongKeun Park, Scientific Reports (2016)

Holographic intravital microscopy for 2-D and 3-D imaging intact circulating blood cells in microcapillaries of live mice

Kyoohyun Kim, Kibaek Choe […] YongKeun Park, Scientific Reports (2016)

Optical characterization of red blood cells from individuals with sickle cell trait and disease in Tanzania using quantitative phase imaging

JaeHwang Jung, Lucas E. Matemba […] YongKeun Park, Scientific Reports (2016)

Optical diffraction tomography using a digital micromirror device for stable measurement of 4-D refractive index tomography of cells

Seungwoo Shin, Kyoohyun Kim […] YongKeun Park, proceeding of SPIE (2016)

Three-dimensional refractive index tomograms and deformability of individual human red blood cells from cord blood of newborn infants and maternal blood

HyunJoo Park, Taegyu Ahn […] YongKeun Park, Journal of Biomedical Optics (2015)

Measurements of morphology and refractive indexes on human downy hairs using three-dimensional quantitative phase imaging

SangYun Lee, Kyoohyun Kim […] YongKeun Park, Journal of Biomedical Optics (2015)

LCD panel characterization by measuring full Jones matrix of individual pixels using polarization-sensitive digital holographic microscopy

Jongchan Park, Hyeonseung Yu […] YongKeun Park, Optics Express (2014)

Common-path diffraction optical tomography for investigation of three-dimensional structures and dynamics of biological cells

Youngchan Kim, Hyoeun Shim […] YongKeun Park, Optics Express (2014)

T cells sense biophysical cues using lamellipodia and filopodia to optimize intraluminal path finding

Kwang Hoon Song, Keon Woo Kwon […] Junsang Doh, Integrative Biology (2014)

Spectro-angular light scattering measurements of individual microscopic objects

JaeHwang Jung and YongKeun Park, Optics Express (2014)

High-resolution three-dimensional imaging of red blood cells parasitized by Plasmodium falciparum and in situ hemozoin crystals using optical diffraction tomography

Kyoohyun Kim, HyeOk Yoon […] YongKeun Park, Journal of Biomedical Optics (2013)

Pf155/RESA protein influences the dynamic microcirculatory behavior of ring-stage Plasmodium falciparum infected red blood cells

Monica Diez-Silva, YongKeun Park […] Subra Suresh, Scientific Reports (2012)

Dynamic spectroscopic phase microscopy for quantifying hemoglobin concentration and dynamic membrane fluctuation in red blood cells

Yunhun Jang, Jaeduck Jang and YongKeun Park, Optics Express (2012)

A Scalable Suspension Platform for Generating High-Density Cultures of Universal Red Blood Cells from Human Induced Pluripotent Stem Cells

Jaichandran Sivalingam, Yu SuE, […] , Benoit Malleret, Steve K.W.Oh, Stem Cell Reports (2021)

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